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dopamine counterbalances serotonin suggesting that alphasynuclein is related to prions Pr

2004-06-14 01:05:07 AM
On Sun, 13 Jun 2004 02:06:57 -0500, Archimedes Plutonium
<a_plutonium@iw.net>wrote:
Quote

If my analogy above holds true then since the symmetry between dopamine
and serotonin suggests some symmetry between Alphasynuclein and Prion
but I am guessing there is no symmetry here.

I need a nice big picture model of these above 4 proteins, actually 6
proteins if we add tau and betaamyloid.

dopamine and serotonin are not proteins. They are neurotransmitters --
small molecules, with molar mass on order of 100 (not tens of
thousands).
Google on any of those names, plus "structure", should yield pictures.
bob
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Re:dopamine counterbalances serotonin suggesting that alphasynuclein is related to prions Pr

Sun, 13 Jun 2004 10:05:07 -0700 Bob wrote:
Quote
On Sun, 13 Jun 2004 02:06:57 -0500, Archimedes Plutonium
<a_plutonium@iw.net>wrote:

>
>If my analogy above holds true then since the symmetry between dopamine
>and serotonin suggests some symmetry between Alphasynuclein and Prion
>but I am guessing there is no symmetry here.
>
>I need a nice big picture model of these above 4 proteins, actually 6
>proteins if we add tau and betaamyloid.
>

dopamine and serotonin are not proteins. They are neurotransmitters --
small molecules, with molar mass on order of 100 (not tens of
thousands).

Google on any of those names, plus "structure", should yield pictures.

bob
Found that dopamine is C8 H11 N O2
Found that serotonin is C10 H12 N2 O
Now I wonder if by looking at those two formulas (and I know this is not
physics of elementary particles with symmetry breaking)
But I wonder, nonetheless, by looking whether we can see the
counterbalancing of dopamine to serotonin so that as one quantity increases
the other decreases and vice versa. That they behave in a inverse or
reverse role. Whether the fact that one has N and the other N2 and one has
O2 and the other O.
But I was not lucky in finding a chemical formula for any of the protein
molecules of Prion, of Alphasynuclein, and of Tau and BetaAmyloid in
Alzheimers. I could only find the fact that Prion is 253 aminoacids long.
So how long is Alphasynuclein in terms of amino acids and also tau and
betaamyloid?
Can someone furnish a formula for these proteins:
Prion:
Alphasynuclein:
Tau (in Alzheimers):
BetaAmyloid (in Alzheimers):
I need a formula to compare dopamine and serotonin formulae
I will be surprized to find, if true, that prion is the most complex
molecule of them all.
The symmetry testing is interesting also in that if Parkinsons is linked
between the amino acids of Dopamine and the protein of AlphaSynuclein. And
if the amino acids of Serotonin and protein of PrP are linked in Prion
diseases. Then the symmetry is broken for Alzheimers for it has no amino
acid link of a neurotransmitter. This would suggest that the Tau is
irrelevant to Alzheimers and that a neurotransmitter has a key role in
Alzheimers. Perhaps serotonin is the neurotransmitter for both Alzheimers
and for prion diseases. In this light, then, Prion disease is just a subset
or a different form of Alzheimers and a analogy would be the virus of
hepatitus which comes in a variety of forms. So that prion disease is a
different form of Alzheimers so long as the neurotransmitter are the same
of serotonin.
What I would like to find out is whether these proteins of Alphasynuclein
can ramp up the manufacture of serotonin or breakdown dopamine. Or whether
prions can ramp up serotonin or breakdown serotonin.
There is another connection in these 3 diseases in that the behaviour of
the victims follows a similar course in Parkinsons of shaking and inability
to walk or stand. In Prion diseases we again have the inability to walk or
stand. And the symmetry is broken in Alzheimers in that walking and
standing seem to last until near the end. Perhaps the neurotransmitter
affected in Alzheimers is not dopamine or serotonin but a different one so
that walking and standing ability lasts longer.
If someone can provide formulas above is much appreciated.
Archimedes Plutonium
www.archimedesplutonium.com
www.iw.net/~a_plutonium
whole entire Universe is just one big atom where dots
of the electron-dot-cloud are galaxies
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Re:dopamine counterbalances serotonin suggesting that alphasynuclein is related to prions Pr

Bob <bbruner@uclink4.berkeley.edu>wrote in message
Quote
On Sun, 13 Jun 2004 02:06:57 -0500, Archimedes Plutonium
<a_plutonium@iw.net>wrote:

>
>If my analogy above holds true then since the symmetry between dopamine
>and serotonin suggests some symmetry between Alphasynuclein and Prion
>but I am guessing there is no symmetry here.
>
>I need a nice big picture model of these above 4 proteins, actually 6
>proteins if we add tau and betaamyloid.
>


dopamine and serotonin are not proteins. They are neurotransmitters --
small molecules, with molar mass on order of 100 (not tens of
thousands).
I'm not sure that Plonkonium can understand this.
Quote
Google on any of those names, plus "structure", should yield pictures.

bob
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